PY-806 PROFESSIONAL TRAINING SYLLABUS

There will be a 4 week professional training or industrial training schdule . at the end of the semester a Proffessional training report submit at the time of practical.there is no theory papers

PY-805 ELECTIVE SYLLABUS PY 8101 PACAKAGING TECHNOLOGY

RGPV B. PHARMACY ELECTIVE PY-805 SYLLABUS

PY 8101  PACAKAGING TECHNOLOGY

• New concepts in pharmaceutical packaging.

• Package system, package design research.

• Packaging materials with special reference to polymers, metals glass and plastics, control of packaging materials.Blister and Strip packaging.

• Testing of containers and closures, Pharmacopoeial tests and specifications.

• Defects in Packages.

• Stability of packages and packaging materials.

• Ancillary materials used in packaging.

• Sterlization of pacakaging materilas.

• Packaging of parenterals, ophthalmics and aerosols.

• Corrugated fiberboard materials, label and leaflets preparation.

• Legal requirement.

PY 8102 FOOD TECHNOLOGY: 

Syllabus to be prepared.

PY 8103 PERFUMES AND COLOURS

 

Sources and method of extraction / preparation of essential oils, flower oils, Gums, Oleoresins, Oleogum resins and Balsams.

• Isolation, Properties and Uses of –Eugenol, Pinene, Linalool, Citral and Geraniol. Deodorization of Ethanol.

• Fixatives-Sources, classification, chemical composition, selection and uses of fixatives.

• Flavoures –Sources and properties of Vanila, Rose, Pineapple, Peppermint, Mango, Raspberry, Orange and Lemon.

• Building of perfumes: Formulation of perfumes, from synthetic substance, sources, composition and properties of Lavender, Rose,Jasmin, Violet, Orris, Cypre, Amber, Carnation, Muguet, Liliac, Acacia, cassia, Narcisssus, Kewra. Incorporation of perfumes incosmetic products lioke creams, lotions, powders, Hair preparations, Nail preparataions, Tooth pastes, Toilet Soaps, BabyPreparations, Lip and other preparations.

• Packaging: Packaging of perfumes including special emphasis on aerosol products.

• Colours, Pigments, Dyes-Classification, uses and preparation of colours solutions/ dispersions incorporations. Detection of colours.

PY 8104 COMMUNITY PHARMACY 

Syllabus to be prepared.

PY 8105 CLINICAL PHARMACY

Syllabus to be prepared.

PY 8106 INDUSTRIAL PHARMACY

Syllabus to be prepared.

PY-804 PHARMACOLOGY –IV (CLINICAL PHARMACY AND DRUG INTERACTIONS) SYLLABUS

RGPV B. PHARMACY PHARMACOLOGY –IV (CLINICAL PHARMACY AND DRUG INTERACTIONS) PY-804 SYLLABUS

Chemotherapy –

•  General principles of chemotherapy

•  Sulfonamides and co-trimaxazole

•  Antibiotics-Penicillin, Cephalosporins, Betalactums tetracyclines, Aminoglycosides, Choloramphenicol, Erythomycin,Quinolones and Miscellaneous antibiotics.

• Chemotherapy of tuberculosis, leprosy, fungal diastase, viral diseases, urinary tract infections and sexually transmitted diseases

• Chemotherapy of malignancy and immunosuppressive agents

• Anti malarials and Anti diarrhoeal 

Basic Concepts of Pharmacotherapya) 

• Clinical Pharmacokinetics Individualization of Drug Therapy.

•  Drug Use During Infancy and in the Elderly ( Paediatrics and Geriatrics)

• Drug use druring Pregnancy.

• Drug induced disease.

• The Basics of Drug interactions.

• General principles of clinical laboratory tests.

Therapeutic Drug Monitoring Concept of essential Drugs and Drug Use, Drug abuse.

Principles of Toxiclogy

• Detination of Poison, general principles of treatment of poisoning particular reference of barbiturates, Opoids,Organophosphorylation and Atropine poisoing.

• Heavy metals and heavy metal antagonists.

To study different screecring methods using various behavioral models

Books recommended
1. Herfindal, E.T. and Hirschman, J.L., Clinical Pharmacy and Therapeutics, William and Wilkins.
2. Katzung, B.G., Basic and Clinical Pharmacology, Prentice Hall International.
3. Laurence, D.R. and Bennet, P.N., Clinical Pharmacology, Churchill Livingstone.

PY-803 PHARMACEUTICAL ANALYSIS-III SYLLABUS

RGPV B. PHARMACY PHARMACEUTICAL ANALYSIS-III PY-803 SYLLABUS

UNIT-I

Doasage forms evaluation as per monograph with special reference to I.P.Development of new analytical methods.

UNIT-II
Concepts in validation, validation of manufacturing and analytical equipment, validation of analytical procedures.
Documentation: Protocols, forms and maintainance of records in pharmaceutical industries, preparation of documents for new drug approval and export registration to United States, United Kingdom, Europe and Africa.Patent processing and its appcations.

UNIT-III
Requirement of GLP, ISO 9000, WHO and U.S. F.D.A.

UNIT-IV
Basic concept of quality assurance, quality assurance system, sources and control of quality variation.In-process quality control tests, IPQC problems in Pharmaceutical Industries, Total quality management.

UNIT-V
Sampling plans, sampling and operating characterictics curves,Interpretation of analytical data.
Regulatory control, regulatory drug analysis.

VIII-P-3 PHARMACEUTICAL ANALYSIS –III PRACTICALS

Evaluation of dosage formulations as per I.P. monographs. Experiments based on theory.

Books Recommended
1. Willing, S. H., IV, Good Manufacturing Practices for Pharmaceuticals, Marcel Dekker Inc., New York.
2. Loftus, B. T. and Nash R., Pharmaceutical Process Validation, Marcel Dekker Inc., New York.
3. Svehla, G. Vogel’s Text Book of Micro and Semi Micro Qualitative Inorganic Analysis, Orient Longman, Hyderabad.
4. Beckett, A.H. and Stenlake, J.B., Practical Pharmaceutical Chemistry, The Athlone Press of the University of London.
5. Pharmacopoeia Of India, Ministry of Health and Family Welfare, Govt. of India, New Delhi.

PY-802 PHARMACEUTICS XII (BIOPHARMACEUTICS AND PHARMACOKINETICS) SYLLABUS

RGPV B. PHARMACY PHARMACEUTICS XII (BIOPHARMACEUTICS AND PHARMACOKINETICS) PY-802 SYLLABUS

 

UNIT-I

Introduction to biopharmaceutics and pharmacokinetics development and their role in drug formulation.Biopharmaceutics

UNIT-II
Definition, passage of drugs across biological barrier, Physiochemical, Biological and Pharmacaceutical factors influencing biopharmaceutical performance of drugs.
1. Gastrointestinal absorption of drugs: Passage of drugs across biological membranes, nature of biological membranes, gastrointestinal absorption mechanisms.
2. Factors affecting drug absorption: Physiological factors, dietary factors, physicochemical factors, pH partition hypothesis, dosage form factors.
3. Methods of studying gastrointestinal absorption: In vitro and in vivo methods.
4. Drug disposition: Distribution in blood, cellular distribution, plasma protein binding, tissue protein binding.Drug Excretion: Routes of drug excretion, renal excretion of drugs, factors affecting renal excretion, biliary and salivary excretionof drugs.

UNIT-III
Drug biotransformation : Pathways of drug metabolism, drug metabolizing enzymes, factors affecting drug metabolism and drugresponse, inhibition and stimulation of drug metabolism.
PharmacokineticsAbsorbtion, distribution, metabolism and excretion of drugs, fluid compartment and circulatory system, protien binding,significance of plasma drug concentration measurement.Compartment Models

UNIT-IV
Model selection criteria, alaika information criterion, one-compartment and two-compartment models, Wagner-Nelson and looRiegelman methods for estimation of absorption constants. Curve fittings, regression procedure and area under blood level curves.
Clinical Pharmacokinetics.Urinary excretions, computation of pharmacokinetic parameters from urine data, haepetic clearance, biliary excretion, excretion ratio, dosage regimen adjustment in patients with and without renal failure, pharmacokinetic drug interactions and theirsignificance in combination therapy.

UNIT-V
Bioavailability and Bioequivalance:Bioavailability and Bio-equivalance, Federal requirements, Methods of determination of bioavailability using blood level and urinary excretion data, design and evaluations, bioavailability assessment.

VIII-P-2-PHARMACEUTICS-XII PRACTICALS
(BIOPHARMACEUTICS AND PHARMACOKINETICS)

Experiments based on theory.Statistical treatment of pharmaceutical data.

Books recommended
1. Gibaldi, M. and Perrier d, Pharmacokinetics, Marcel Decker, New York.
2. Notari, R.E., Biopharmaceutics and Pharmacokinetics-An Introduction, Marcel Decker, New York.
3. Jaiswal , Brahmankar

PY-801 PHARMACEUTICS –XI (PHARMACEUTICAL TECHNOLOGY – II) SYLLABUS

RGPV B. PHARMACY PHARMACEUTICS –XI (PHARMACEUTICAL TECHNOLOGY – II) PY-801 SYLLABUS

UNIT-I
Design, development, formulation and evaluation of controlled release formulations. Carriers for drug delivery systems, Prodrugs.

UNIT-II
Microencapsulation: Theory, methods, technology and applications. 

UNIT-III
Transdermal Drug Delivery Systems: Theory, formulation and evaluation.

UNIT-IV
Targeted Drug Delivery Systems: Concept of drug targetting, importance in therapeutics, methods in drug targeting, Nanoparticles, Liposomes, Resealed Erythrocytes etc.

UNIT-V
Implants and Inserts: Types, design and evaluation, Osmotic pump.Packaginging of Pharmaceutical Products and Cosmetics: Packaging components, types, specifications and methods of evaluation,stability aspects of packaging, packaging equipment, factors influencing choice of containers, legal and other official requirements for containers, Packaging testing.

VIII-P-1 PHARMACEUTICS-XI PRACTICALS
(PHARMACEUTICAL TECHNOLOGY II)

Formulations, evaluations and stability testing of preparations concerning dosage forms mentioned in theory.

Books Recommended
1. Rawlins, E.A., Text Book Of Pharmaceutics, Bailliere Tindall.
2. Lachman, L. , Liberman, H.A. and Kanig, J.L.,The Theory and Practice of Industrial Pharmacy, Lea and Febiger, Philadelphia.
3. Liberman, H.A., lachman, L. and Ker Inc. New York.
4. Pharmacopoeia Of India, Ministry of Health and family Welfare, Govt. of India, New Delhi.
5. Avis, K.E., Lachman, L. and Liberman, H.A., Pharmaceutical Dosage Forms-Parenteral Medication Vol.1-2, Marcel Decker
Inc., New York.
6. Banker G.S. and Rhode C.T., Modern Pharmaceutics, Marcell Decker Inc., New York.
7. Bean, H.S., Beckeet, A.H. and Carless, A.H., Advances in Pharmaceutical Sciences, Vol.1-4, Academic Press, London.